When it comes to fluorescence imaging of thick tissue, two-photon excitation microscopy
has two major advantages. The combination of increased penetration depth
and reduced tissue damage constitutes two-photon microscopy the gold standard
for in vivo imaging. (See here for an introduction to multiphoton fluorescence microscopy).
TILL’s Two-Photon microscopes combine all the advantages in a fast and accurate, but still
flexible way. The two-photon laser scanning platforms in combination with
the novel voice coil-based focus drive enables 3-D scans of unprecedented volume
and accuracy.
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